Types and Stages of Breast Cancer

Breast cancer staging defines the severity of cancer in the body which is treated with either chemotherapy, hormone therapy, or drugs. It has both medical and pathologic staging classifications for breast cancer. The pathologic stage is identified by examining tissue removed through an operation. If surgery is not possible, sometimes right away cancer will be given a clinical stage instead. Imaging tests like x-rays, CT scans, MRIs, ultrasound, and PET scans may also give information about how much and where cancer is in the body. In the system called TNM, every cancer is assigned a letter or number to describe the tumor, node, and metastases. In stage grouping, once the values for T, N, and M have been determined, they are combined to allot an overall stage.

  • Breast Cancer Awareness
  • Staging / Classification of Breast Cancer

Breast Cancer and Cell Biology

A cancer cell is a cell that multiplies out of control. Unlike normal cells, cancer cells disregard signals to stop dividing, to focus, or to die and be shed. Growing in a disorderly manner and incapable to recognize its own accepted boundary, the cancer cells may spread to zones of the body where they do not belong. Cancer cells are very complex cells and it is challenging for clinicians to manage breast cancer therapy. In multidrug resistance events membrane transporters plays a foremost part, which are the cell’s first line of contact with anticancer drugs. So, cell construction and biological characteristics of the cell leads to drug-resistant and lead to a reduction in the intracellular activity of drugs.

  • Cell Biology of Cancer
  • Breast Cancer Diagnosis
  • Mammography
  • MRI and Ultrasound Detection
  • Biopsy & Lab tests

Breast Cancer and Immunology

Immunotherapy improves the aftereffect of clinical treatment in breast cancer patients. Targeted therapy is the approach used to directly target tumor cells, by which side effects of immunotherapy can be reduced. Immunotherapy is category of treatments that take benefit of a person's own immune system aid to kill cancer cells. There are presently three permitted immunotherapy choices for patients with tumors that overexpress a protein receptor

  • Immunotherapy for Breast Cancer
  • Mechanism of Immune evasion
  • Cancer Immunology

Types of Cancer Treatment

There are many forms of cancer treatment. The types of treatment that you take depends on the nature of cancer you have and its severity. Some people with cancer will undergo only one treatment procedure. But most people have a blend of treatments, such as surgery with chemotherapy and/or radiation therapy. There are certain effective modes like immunotherapy, targeted therapy, or hormone therapy conducive for certain type of cancer

  • Breast Cancer Surgery
  • Radiation Therapy & Chemotherapy
  • Immunotherapy to Treat Cancer
  • Targeted Therapy & Hormone Therapy
  • Stem Cell Transplant
  • Precision Medicine

Breast Cancer Research

Indications of breast cancer are the similar in men like women. Maximum of the men are not aware of this and the treatment of breast cancer males is mostly tardy as compared to females because of obliviousness. Major risk features of breast cancer that occur are during the premenopausal years, the rate of upsurge in occurrence is common everywhere in the world, roughly about 8%-9% per year, breastfeeding each kid for less than 6 months, and physical idleness, are each related to an predictable 3% of female breast cancer cases. Lifestyle factors including overweight and obesity, alcohol and certain work-related exposures also lead to breast cancer.

  • Male Breast Cancer Research
  • Epidemiology of Breast Cancer And Risk Factors
  • Diet and Lifestyle Effect on Breast Cancer

Breast Cancer Care

Breast cancer management takes diverse methods that depend on the physical and biological characteristics of the disease, age, overall fitness and individual preferences of the patient. Local therapy and systemic treatment are the 2 basic types of treatment. The backbone of breast cancer management is surgery for the local and regional tumor, trailed by a blend of chemotherapy, radiotherapy, endocrine therapy, and targeted therapy. Nurses play a significant part during the treatment of breast cancer because they can support the patient to build physically and mentally. They can instruct patients about risk factors, reliable ways to decrease them. Nurses involved in breast cancer care have an influence on the early encounter of breast cancer, treatment who serve as supporters for womankind with the disease.

  • Breast Cancer Nursing
  • Breast Cancer Management

Breast Cancer Surgery

The removal of cancer cells from breast is known as Breast cancer surgery, which is the main key component for breast cancer treatment. Chemotherapy, Hormone therapy, radiation therapy, and targeted therapy are the other types of treatments that are used along with the surgery. This surgery might be an option for breast cancer people to reduce the risk of future breast cancer growth. The surgical removal of the breast is termed as Mastectomy. This type of surgery can help in removing one or both the breast partially or completely. It can be a preventive measure for high-risk patients. The cancer surgery depends on the size and stage of the cancer

  • Mastectomy
  • Lumpectomy
  • Breast reconstruction with flap surgery
  • Sentinel node biopsy
  • Breast reconstruction with implants

Advancements in Breast cancer treatment

To enhance the breast cancer treatment, screening and early detection are the only option. The advances in imaging pave way for more improvements in early detection and screening. The breast tomosynthesis also called 3-D mammography are one such recent developments to know the size & growth of cancer cells. Other recent developments are Molecular breast imaging (MBI) and Breast specific gamma imaging (BSGI). Treatments are possible for the HR-Positive Breast Cancer and HER2-Positive Breast Cancer, but not triple-negative breast cancer which is hard to treat since both HER2 positive and HR-positive are absent.

Immunotherapy for Breast Cancer

The immune system is a complex network and cells which fight against all infections. The immunotherapy involves stimulating our immune system to identify and destroy cancer cells in a way more effective manner. Stimulation is done by the usage of medicines or drugs. The immune system can keep a record of microbe types, that are destroyed and can keep itself from been destroying the normal cells. To maintain this record, they engage the checkpoints. The T cells identify and link with partner protein on tumor cells. These partner proteins are called immune checkpoint proteins. They send an 'OFF' signal to the T cells when the checkpoint and partner protein combine. The immunotherapy drug works by blocking the checkpoint proteins from linking with the partner proteins, that can stop the OFF signal from being sent resulting in destroying the cancer cells. Drugs used for targeting the HER2 pathway helps in alerting the immune system to destroy cancer cells. The drugs can be classified based upon the stage of the cancer.

  • Pertuzumab (Perjeta®)
  • Trastuzumab (Herceptin®)
  • Trastuzumab deruxtecan (Enhertu™)
  • Trastuzumab emtansine (Kadcyla®)

Track 13: Computational Brain and Brain engineering

Computational Theory of Mind (CTM) refers to the various views that hold the theory that the human mind is an information processing system and that cognition and consciousness together are a form of computation. Computational approaches include statistics, computer simulations, mathematics, and abstractions which are used across many subfields of Breasst Cancer including development, physiology, structure, and cognitive abilities of the nervous system

Track 14: Addictive Disorders & Substance Abuse

Drug addiction may be a neurological disorder that's characterized by compulsive drug seeking, despite of its harmful consequences. It causes changes within the traditional activity of the system nervous damaging the nerve tissues, killing neurons and this results in dysregulation of neural system. Thus uncontrolled drug use ends up in toxicity of brain. Some of the activity effects of addiction embody psychosis, Aggressiveness, thoughtfulness, and Loss of Self-Control. Prescription drugs that area unit usually abused area unit sleep medicines and opioids. In reality, addiction may be a complicated illness, and quitting sometimes takes quite smart intentions or a powerful can.

Track 15: Neurology Treatment

In order to accelerate the discoveries of novel diagnostic medical aid, gathering of neurology researchers is inspired so as to debate on neural disorder and treatment, maturation, Nerve injury and repair and headache, and last but not the least some new therapeutics evolved for neurological disorders. A calculable 72, 120 new cases of primary brain tumors are expected to be diagnosed in 2012 that includes both malignant and non-malignant brain tumors. Based on the prevalence of diseases, Conference focuses on advances in medical specialty treatment.

Session 6 : Targeting neuronal circuits

Track 16: Cerebrospinal complications

Cerebrospinal fluid (CSF) may be a clear, colorless bodily fluid found within the brain and funiculus. Cerebrospinal fluid has 3 main functions: It protects brain and funiculus from trauma, provides nutrients to system nervous tissue, removes waste product from cerebral metabolism.CSF leaks occur through a communication between the liner of the brain and therefore the nose. These communications may occur spontaneously or result from trauma or prior Sino nasal surgery. Complications could occur if the cause is surgery or trauma. Infections once surgery or trauma will result in infectious disease and heavy complications, such as swelling of the brain. Most CSF leaks a complication of a centesis or surgery.

Track 17: Case Reports in Neurological Medicine

Case report guide in latest years has seen significance a price of case reports in clinical medication has grown up. Not all area of medical studies is amenable to very large scientific trials. Many topics are higher addressed by more precise descriptions of multi-factorial additives that make contributions to effects, and those are regions wherein case reports shine. Writing a case or assortment reinforces several aspects of the medical coaching method, and house body of staff area unit advocated investigating, writing, and putting up reports.